1 Department of pharm D, CMR College of Pharmacy, Kandlakoya, Hyderabad, Telangana, India – 501401.
2 Department of Pharmaceutical Sciences, Kandlakoya, Hyderabad, Telangana, India – 501401.
International Journal of Science and Research Archive, 2025, 17(01), 570-572
Article DOI: 10.30574/ijsra.2025.17.1.1900
Received on 25 May 2025; revised on 01 July 2025; accepted on 04 July 2025
Systemic sclerosis (SSc) is a systemic autoimmune disease in which gastrointestinal manifestations are a frequent complication. In as many as 90% of cases, there is intestinal involvement. The oesophagus and the anorectal tract are the regions most impacted. Digestion-related discomfort is most commonly caused by reflux, heartburn, and dysmotility. The development of faecal incontinence is significantly influenced by disordered anorectal function, which can happen early in the course of SSc. Oesophageal dysmotility, heartburn, dysphagia, nausea, vomiting, diarrhoea, constipation, bloating/distension, and faecal incontinence are among the symptoms of scleroderma that are frequently experienced. An endoscopy examination and manometry measurements are used to diagnose systemic sclerosis. Proton pump inhibitors, h2 receptor blockers, prokinetics, antibiotics, and laxatives are currently advised for the treatment of gastrointestinal disorders in SSc patients.
Scleroderma; Gastritis; Autoimmune Disorder; Proton Pump Inhibitors; GERD; Endoscopy
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Vankodoth Sireesha, Asiya Sultana, P. Ramya Sri, Ayesha Mateen and T. Rama Rao. Scleroderma present with acute gastritis: A rare case report. International Journal of Science and Research Archive, 2025, 17(01), 570-572. Article DOI: https://doi.org/10.30574/ijsra.2025.17.1.1900.
Copyright © 2025 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0







