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ISSN Approved Journal || eISSN: 2582-8185 || CODEN: IJSRO2 || Impact Factor 8.2 || Google Scholar and CrossRef Indexed

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Research and review articles are invited for publication in January 2026 (Volume 18, Issue 1)

Exploring the effects of beta vulgaris on GLP-1 secretion and metabolism: Mini review

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  • Exploring the effects of beta vulgaris on GLP-1 secretion and metabolism: Mini review

Sushma Papireddypalli, B Dhanush, T R Harini Ganga, Geethanjali Bukke and Somasekhar Reddy Kanala *

Department of Pharmacology, Raghavendra Institute of Pharmaceutical Education and Research (RIPER), Krishnamreddy Palli Cross, Chiyyedu (Post), Anantapur, Andhrapradesh, India – 515 721.

Review Article

International Journal of Science and Research Archive, 2025, 15(01), 275-282

Article DOI: 10.30574/ijsra.2025.15.1.0924

DOI url: https://doi.org/10.30574/ijsra.2025.15.1.0924

Received on 24 February 2025; revised on 01 April 2025; accepted on 03 April 2025

Beetroot, also known as Beta vulgaris, is a popular root vegetable that is valued for both its medicinal and nutritional qualities. According to recent research, it may play a role in regulating insulin secretion and glucose metabolism, particularly in how it regulates the release of glucagon-like peptide-1 (GLP-1). Blood glucose levels are regulated by the crucial incretin hormone GLP-1, which increases insulin production in response to food intake. Explore how Beta vulgaris affects GLP-1 secretion and metabolism in general. Beta vulgaris's bioactive substances, including betalains, nitrates, and fiber, have been demonstrated to have antioxidant, vasodilatory, and anti-inflammatory properties that may affect metabolic processes. The study explores the effects of Beta Vulgaris ingestion on GLP-1 levels and its possible implications for enhancing insulin sensitivity and glucose homeostasis by looking at both in vitro and in vivo models. The study also assesses the wider metabolic impacts, such as modifications to lipid profiles, obesity, and mitochondrial function. The findings could contribute to a better understanding of Beta vulgaris's function in metabolic health and its potential as a dietary intervention for those with obesity, type 2 diabetes, and insulin resistance. This study opens the door for more research and possible treatment uses in metabolic diseases by clarifying the molecular mechanisms through which Beta vulgaris may affect GLP-1 production and metabolic control.

Beta vulgaris; Glucagon like peptide-1; Type 2 diabetes; Incretin hormone; Insulin resistance; Betalains

https://journalijsra.com/sites/default/files/fulltext_pdf/IJSRA-2025-0924.pdf

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Sushma Papireddypalli, B Dhanush, T R Harini Ganga, Geethanjali Bukke and Somasekhar Reddy Kanala. Exploring the effects of beta vulgaris on GLP-1 secretion and metabolism: Mini review. International Journal of Science and Research Archive, 2025, 15(01), 275-282. Article DOI: https://doi.org/10.30574/ijsra.2025.15.1.0924.

Copyright © 2025 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0

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