Double Warthin’s Tumor: Case report and our 4-year experience

The purpose of this study was to determine the clinical and histological features, as well as the treatment approach, of Warthin’s Tumor. Albrecht–Artz–Warthin Tumor is a benign neoplasm of the salivary glands, historically known as papillary cystadenoma lymphomatosum. It accounts for approximately 0.6–11% of all salivary gland neoplasms and is more common in men during the 6th and 7th decades of life. This tumor almost exclusively occurs in the parotid gland and can present as bilateral or multifocal lesions, and it manifests as a painless swelling, usually within the lower portion of the parotid gland.

The aim of this work was to describe the clinical and histological characteristics of Warthin’s Tumor, providing useful information for the differential diagnosis with other salivary gland neoplasms. Data from the literature were compared with ours, collected over a ten-year clinical activity in the Oral and Maxillofacial Surgery Unit of "Our Lady of Good Counsel Hospital".

The prognosis of Warthin’s Tumor (W.T.) is certainly favorable, with nearly 100% restitutio ad integrum. Between May 2022 and November 2025, we reported 3 diagnoses of Warthin’s Tumor. The incidence of W.T. in our patient sample was 0.181%.

In conclusion, Warthin’s Tumor is a benign salivary gland tumor that requires accurate diagnosis, complete surgical excision, and adequate follow-up, as malignant transformation, although rare, remains possible.