Malla Reddy College of Pharmacy, Maisammaguda, Dhulapally, Kompally(PO), Secunderabad-500100.
International Journal of Science and Research Archive, 2025, 14(02), 1626-1634
Article DOI: 10.30574/ijsra.2025.14.2.0503
Received on 09 January 2025; revised on 20 February 2025; accepted on 23 February 2025
Achieving ideal glycemic control is essential for those with Type 2 Diabetes Mellitus (T2DM), as is avoiding hypoglycemia, controlling body weight, and lowering cardiovascular risk. A prospective treatment strategy that meets these demands is provided by agonists of the Glucagon-Like Peptide-1 receptor. These drugs block glucagon secretion, slow stomach emptying, decrease appetite, and increase glucose-dependent insulin secretion, all of which help control weight and minimize the risk of hypoglycemic episodes. Furthermore, a number of GLP-1 receptor agonists have shown promising increase in renal and cardiovascular health. Patients might have a more convenient treatment regimen because they are accessible as weekly or daily injections. Furthermore, a lower risk of cardiovascular disease has been associated with some GLP-1 receptor agonists. According to recent studies, these substances may also have a number of neuroprotective advantages, such as increasing neurogenesis, lowering cell death, shielding neurons from oxidative stress, and lowering neuroinflammation in a range of neurological disorders. These substances are therefore being investigated as potential therapies for neurodegenerative illnesses like Parkinson's and Alzheimer's.
Semaglutide; Weight Loss; GLP-1 Receptor Agonist; Type 2 Diabetes(T2DM); Parkinson’s Disease; Alzheimer’s Disease
Preview Article PDF
Shaik Parveen, Ajay Boddu and Sharanya Narala.Beyond glycemic control: semaglutide's multifaceted impact on metabolic health. International Journal of Science and Research Archive, 2025, 14(02), 1626-1634. Article DOI: https://doi.org/10.30574/ijsra.2025.14.2.0503.
Copyright © 2025 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0







