Pravara Rural College OF Pharmacy, Loni, Department of Parmacognosy, Dist. Ahmednagar, Tal. Rahata Maharashtra, India.
International Journal of Science and Research Archive, 2025, 14(03), 496-503
Article DOI: 10.30574/ijsra.2025.14.3.0675
Received on 29 January 2025; revised on 07 March 2025; accepted on 10 March 2025
Herbal formulations are increasingly preferred over synthetic alternatives due to their natural origin and minimal side effects. This study aims to develop a safe and effective polyherbal toothpaste using Shikakai (Acacia concinna) extract as a natural foaming agent, replacing synthetic surfactants like Sodium Isethionate. The formulation incorporates Neem (Azadirachta indica), Clove (Syzygium aromaticum), Turmeric (Curcuma longa, API: Curcumin), and Aloe Vera (Aloe barbadensis), which offer multiple medicinal benefits such as reducing dental plaque, gingivitis, cavities, gum diseases, and mouth ulcers. Calcium Carbonate acts as a mild abrasive, while Menthol and Honey enhance freshness and antimicrobial efficacy.
The surfactant is naturally derived from Shikakai pods, ensuring good foaming ability and optimal cleaning efficiency. The laboratory formulation was evaluated for pH, spreadability, homogeneity, stability, foaming ability, extrudability, and moisture content. In vitro studies assessed its antibacterial activity against both Gram-positive and Gram-negative bacteria, demonstrating significant zones of inhibition. The resulting formulation exhibited a brownish aromatic appearance, effective foaming, and strong antimicrobial potential, making it a safe and efficient herbal alternative for oral hygiene.
Polyherbal; Toothpaste; Organoleptic; Turmeric; Sodium isethionate; Antimicrobial
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Jatin Rajendra Kudnar, Swapnil Sanjay Mirajgave, Nandini Vitthal Kumavat and Gurudeo Shivaji Mandhare. Natural oral care: Formulation and evaluation of a polyherbal toothpaste. International Journal of Science and Research Archive, 2025, 14(03), 496-503. Article DOI: https://doi.org/10.30574/ijsra.2025.14.3.0675.
Copyright © 2025 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0







